Wet granulation of a fine cohesive powder classified into Geldart Group C was conducted by the developed tapered rotating fluidized bed, and its performance as a granulator for handling a fine
Division of Pharmaceutical Technology, School of Pharmacy, University of Athens, Panepistimiopolis, Zografou, Athens 157 71, Greece; Telephone: (301) 727- 4023; Fax: (301) 727-4027; E-mail: rekkas@pharm.uoa.gr 1 Pelletization by means of wet granulation in a fluid-bed weight basis (dg) and the geometric SD (σg) were rotary processor is a Pelletization by means of wet granulation in a fluid-bed rotary processor is a multivariable process in which several factors affect the final characteristics of the pellets produced. Therefore Using the granulation disk, their results proved that the highest grade of the material granulation was obtained with the rotational speed of 14 rpm, while our results were acquired by 20 rpm. Table 4 shows, that the toughness of granules of coal fly ash was on average 2.92 N, and was higher than made from lignite ash (1.46 N), in contrast to 3.1.2 Dry Granulation, Pelletization, and Tableting. The disadvantage of wet granulation is that it typically results in fewer density granules than dry granulation. Although dry granulation is an effective method to obtain high-density shapes with higher mechanical strengths, there is usually a trade-off between performance and mechanical 3t3z05. 87 373 443 44 233 130 461 145 432